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Our OPC capsules contain a pure grape seed extract from grapes, which is particularly rich in valuable secondary plant substances. These are colorants, fragrances and flavoringswhich are contained in plants and have a beneficial effect on health. OPC stands for oligomeric proanthocyanidins, which contain plant substances such as bioflavonoids and polyphenols.
1 capsule contains 190 mg OPC. To get the same amount from food, you would need to consume 633 g of grape seeds.
Thanks to a special extraction process, the OPC capsules from Herbano contain an above-average content of pure of pure OPC of 95 %.
This corresponds to an impressive 190 mg of pure OPC per capsule!
The degree of purity determines the concentration in which the active ingredients are present. The higher this is, the better the body can absorb the vital substances.
Our OPC capsules also contain natural vitamin C from the acerola cherry. This effective combination of nutrients creates a highly effective duo that contributes in particular to improving immune function and also increases the antioxidant protective effect. Because would you have thought that the effect of vitamin C in combination with OPC is drastically enhanced?
Test results confirm this: Researcher Professor Masquelier and his team found that the effect of OPC actually improved 10-fold when vitamin C was added. 10-fold improvement!
➤ Thanks to the clever combination of OPC and vitamin C, you can benefit from a 10-fold increase in effect!
Even in nature, OPC only occurs together with vitamin C. In grapes, for example, the grape seeds with their OPC content are surrounded by pulp with vitamin C.
OPC has an impressively high bioavailability. This means that it enters the bloodstream easily and very quickly - usually within 15 to 30 minutes after ingestion. At the same time, OPC has the ability to pass the blood-brain barrier unhindered and thus also protect the brain from oxidative stress. brain from oxidative stress.
But it is not only in the brain that OPC can protect the cells. In this context, research has shown that OPC is an effective agent against oxidative damage throughout the body. throughout the body. This is because the powerful antioxidant specifically helps to slow down the slow down the ageing process. It binds the free radicals in the body and prevents them from causing further damage. This strengthens the immune system and protects the body from numerous diseases.
OPC is known to support the can support the treatment of cancer . Research has already done a great deal of work in this area, so that a large number of representative studies on the effect of OPC on cancer cells already exist:
While cosmetic products only work in the outermost layers of the skin, OPC capsules can also support the skin from the inside thanks to the antioxidants they contain. antioxidants also support the skin from the inside.
Antioxidants protect the cells in this area from free radicals, which which can arise as a result of various factors, such as
Free radicals are responsible for attacking and damaging skin and body cells.
More and more people are spending many hours a day in front of a screen - whether on their cell phone, TV or computer, whether at work or at home. However, this is damaging their eyes, which ultimately leads to an increase in a wide variety of eye diseases.
➤ Macular degeneration is the most common cause of vision loss: in Europe, as many as 26% of the population aged 50 and over suffer from this eye disease.
Interestingly, in one study it was observed that the total cholesterol level after taking OPC capsules within eight weeks lowered. The researchers concluded that taking OPC capsules can reduce the risk of atherosclerosis and other cardiovascular diseases in people with slightly elevated cholesterol levels.
In a number of small studies, the intake of OPC capsules was associated with a significant reduction in blood pressure associated. At the University of California in Davis, two studies were carried out. One study examined test subjects who suffered from metabolic syndrome. The participants in the other study all suffered from mild hypertension). Both studies came to the conclusion that OPC reduces both the both systolic and diastolic blood pressure.
Healthy, full and beautiful hair - who doesn't want that?
Fortunately, experience shows that OPC is extremely well suited to stimulating hair growth. stimulate hair growth.
OPC can actually also be used for allergies, as it inhibits enzymes that would otherwise lead to the release of histamines. release of histamines and thus contribute to allergic symptoms.
One study investigated this effect in asthmatic mice. After just 8 weeks, a significant improvement in the inflammation levels of the airways and lungs was observed. This indicates that OPC plays an important role in the treatment of asthma. asthma treatment could play.
Ideally, grape seed extract should be taken on an empty stomach as it can then be better absorbed by the body - half an hour before breakfast in the morning is sufficient. If you have a very sensitive stomach stomach, it is advisable to take the capsule with food with food.
Human studies have shown that OPC from grape seed extract is very well tolerated and side effects are normally very rare. When you start taking it, experience has shown that in some cases there may be an initial aggravation. initial aggravation of symptoms, which may include headaches or similar complaints.
You should not take OPC if you:
Recommended intake OPC capsules:
Do not exceed the recommended daily intake.Food supplements are not a substitute for a balanced and varied diet.Store in a cool, dry place away from light. Keep out of the reach of small children.
As this is a product of natural origin, there may be slight variations in shape and color. However, these have no influence on the excellent quality of the ingredients.
Composition of the OPC capsules:
Acerola berry extract (Malpighia punicifolia), grape seed extract (Vitis vinifera), hydroxypropyl methylcellulose (capsule shell)
Quantities per capsule:
glutenfrei
laktosefrei
ohnegelatin
vegan
OPC is a powerful antioxidant that protects the health of our cells and prevents oxidative damage. This makes OPC a protective shield for our skin and eyes, a supporter for our cardiovascular system and also prevents hair loss.
OPC is obtained from grape seeds. The polyphenols they contain protect our cells from oxidation and disease. One Herbano OPC capsule contains 190 mg OPC.
The OPC content is determined using the UV method. This is the standard method used by most manufacturers. This makes it possible to compare products across manufacturers.
Sources (in English):
Savdan, M., Çakır, M., Vatansev, H., Küçükkartallar, T., Tekin, A. & Tavlı, Ş. (2017, June). Preventing oxygen free radical damage by proanthocyanidin in obstructive jaundice. Turkish journal of surgery, 33(2):62-68, doi: 10.5152/turkjsurg.2017.3337
Bagchi, D., Bagchi, M., Stohs, S. J., Das, D. K., Ray, S. D., Kuszynski, C. A. et al. (2000, August). Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention, Toxicology, 148(2-3):187-97
Shi, J., Yu, J., Pohorly, J. E. & Kakuda, Y. (2003). Polyphenolics in grape seeds-biochemistry and functionallity. Journal of medicinal food, 6(4):291-9, doi: 10.1089/109662003772519831
Bagchi, D., Garg, A., Krohn, R. L., Bagchi, M., Tran, M. X. & Stohs S. J. (1997, February). Oxygen free radical scavenging abilities of vitamins C and E, and a grape seed proanthocyanidin extract in vitro. Research Communications in Molecular Pathology and Pharmacology, 95(2):179-89
Mao J. T., Smoake J., Park H. K., Lu Q. Y. & Xue B. (2016, December). Grape Seed Procyanidin Extract Mediates Antineoplastic Effects against Lung Cancer via Modulations of Prostacyclin and 15-HETE Eicosanoid Pathways. Cancer Prev Res (Phila), 9(12):925-932, doi: 10.1158/1940-6207.CAPR-16-0122
Sano A. (2017, October). Safety assessment of 4-week oral intake of proanthocyanidin-rich grape seed extract in healthy subjects. Food Chem Toxicol, 108(Pt B):519-523, doi: 10.1016/j.fct.2016.11.021
Argani H., Ghorbanihaghio A., Vatankhahan H., Rashtchizadeh N., Raeisi S. & Ilghami H. (2016, May). The effect of red grape seed extract on serum paraoxonase activity in patients with mild to moderate hyperlipidemia. Sao Paulo Med J, 134(3):234-9, doi: 10.1590/1516-3180.2015.01702312.
Park E., Edirisinghe I., Choy Y. Y., Waterhouse A. & Burton-Freeman B. (2016, January). Effects of grape seed extract beverage on blood pressure and metabolic indices in individuals with pre-hypertension: a randomised, double-blinded, two-arm, parallel, placebo-controlled trial. Br J Nutr, 115(2):226-38, doi: 10.1017/S0007114515004328
Chen B. H., Hung M. H., Chen J. Y., Chang H. W., Yu M. L. Wan L. et al. (2012, May). Anti-allergic activity of grapeseed extract (GSE) on RBL-2H3 mast cells, Elsevier, 968-974, doi: 10.1016/j.foodchem.2011.11.079, Verfügbar unter [https://www.sciencedirect.com/science/article/pii/S030881461101661X]
Lee T., Kwon H. S., Bang B. R., Lee Y. S., Park M. Y., Moon K. A. et al. (2012, December). Grape seed proanthocyanidin extract attenuates allergic inflammation in murine models of asthma. J Clin Immunol, 32(6):1292-304, doi: 10.1007/s10875-012-9742-8
Wahner-Roedler D. L., Bauer B. A., Loehrer L. L., Cha S. S., Hoskin T. L. & Olson J. E. (2014, June). The effect of grape seed extract on estrogen levels of postmenopausal women: a pilot study. J Diet Suppl, 11(2):184-97, doi: 10.3109/19390211.2013.859220
Ward N. C., Hodgson J. M., Croft K. D., Burke V., Beilin L. J. & Puddey I. B. (2005, February). The combination of vitamin C and grape-seed polyphenols increases blood pressure: a randomized, double-blind, placebo-controlled trial. J Hypertens, 23(2):427-34
Terauchi M., Horiguchi N., Kajiyama A., Akiyoshi M., Owa Y., Kato K. et al. (2014, September). Effects of grape seed proanthocyanidin extract on menopausal symptoms, body composition, and cardiovascular parameters in middle-aged women: a randomized, double-blind, placebo-controlled pilot study. Menopause, 21(9):990-6, doi: 10.1097/GME.0000000000000200
Ras R. T., Zock P. L., Zebreos Y. E., Johnston N. R., Webb D. J. & Draijer R. (2013, December). Effect of polyphenol-rich grape seed extract on ambulatory blood pressure in subjects with pre- and stage I hypertension. Br J Nutr, 110(12):2234-41, doi: 10.1017/S000711451300161X
Kar P., Laight D., Pooprai H. K., Shaw K. M. & Cummings M. (2009, May). Effects of grape seed extract in Type 2 diabetic subjects at high cardiovascular risk: a double blind randomized placebo controlled trial examining metabolic markers, vascular tone, inflammation, oxidative stress and [von Google zensierter Begriff] sensitivity. Diabet Med, 26(5):526-31, doi: 10.1111/j.1464-5491.2009.02727.x
Kaur M., Singh R. P., Gu M., Agarwal R. & Agarwal C. (2006, October). Grape seed extract inhibits in vitro and in vivo growth of human colorectal carcinoma cells. Clin Cancer Res, 12(20 Pt 1):6194-202, doi: 10.1158/1078-0432.CCR-06-1465
Kaur M., Agarwal C. & Agarwal R. (2009, September). Anticancer and Cancer Chemopreventive Potential of Grape Seed Extract and Other Grape-Based Products. J Nutr, 139(9): 1806S–1812S, doi: 10.3945/jn.109.106864
Bagchi D., Bagchi M., Stohs S. J., Das D. K., Ray S. D., Zuszynski C. A. et al. (2000, August). Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention. Toxicology, 148(2-3):187-97
Sapwarobol S., Adisakwattana S., Changpeng S., Ratanawachirin W., Tanruttanawong K. & Boonyarit W. (2012, July-September). Postprandial blood glucose response to grape seed extract in healthy participants: A pilot study. Pharmacogn Mag, 8(31): 192–196, doi: 10.4103/0973-1296.99283
Bagchi D., Sen C. K., Ray S. D., Das D. K., Bagchi M., Preuss H. G. et al. (2003, February-March). Molecular mechanisms of cardioprotection by a novel grape seed proanthocyanidin extract. Mutat Res, 523-524:87-97
Kar P., Laight D., Rooprai H. K., Shaw K. M. & Cummings M. (2009, May). Effects of grape seed extract in Type 2 diabetic subjects at high cardiovascular risk: a double blind randomized placebo controlled trial examining metabolic markers, vascular tone, inflammation, oxidative stress and [von Google zensierter Begriff] sensitivity. Diabet Med, 26(5):526-31, doi: 10.1111/j.1464-5491.2009.02727.x
Bagchi D., Garg A., Krohn R. L., Bagchi M., Tran M. X. & Stohs S. J. (1997, February). Oxygen free radical scavenging abilities of vitamins C and E, and a grape seed proanthocyanidin extract in vitro. Res Commun Mol Pathol Pharmacol, 95(2):179-89
Zhao J., Wang J., Chen Y. & Agarwal R. (1999, September). Anti-tumor-promoting activity of a polyphenolic fraction isolated from grape seeds in the mouse skin two-stage initiation-promotion protocol and identification of procyanidin B5-3'-gallate as the most effective antioxidant constituent. Carcinogenesis, 20(9):1737-45.
Praphasawat, R., Klungsupya, P., Muangman, T., Laovitthayanggoon, S., Arunpairojana, V. & Himakoun, L. (2011). Antimutagenicity and antioxidative DNA damage properties of oligomeric proanthocyanidins from Thai grape seeds in TK6 cells. Asian Pacific Journal of Cancer Prevention: APJCP, 12(5):1317-21
Zi, S. X., Ma, H. J., Li, Y., Liu, W., Yang, Q. Q., Zhao, G. et al. (2009, February). Oligomeric proanthocyanidins from grape seeds effectively inhibit ultraviolet-induced melanogenesis of human melanocytes in vitro. International Journal of Molecular Medicine, 23(2):197-204
Lee T, Kwon HS, Bang BR, et al. Grape seed proanthocyanidin extract attenuates allergic inflammation in murine models of asthma. J Clin Immunol. 2012;32(6):1292-1304. doi:10.1007/s10875-012-9742-8
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OPC grape seed extract capsules - high dose - OPC from french grapes with vitamin C