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5 HTP capsules 200mg - from Griffonia - highly dosed - laboratory tested - without undesirable additives
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Hair Active Capsules with fenugreek - effective nutrient complex with biotin & zinc - to promote hair growth
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MSM capsules - 500mg high-dose methylsulfonylmethane - laboratory tested - 100% ultra pure
Rhodiola capsules -100 % pure extract - high dosage - German premium quality - laboratory tested
Spermidine capsules - wheat germ extract - uniquely HIGH DOSAGE with 8mg spermidine per capsule
We put our joints under strain every day in a variety of ways, but unfortunately we also lose cartilage substance as we get older. These factors inevitably make themselves felt at some point: Joint mobility decreases and joint diseases, such as arthritis and arthrosis have an easy time of it. With our special joint formula, we provide you with a valuable method as a solution to precisely this problem, which you can use to effectively strengthen the health of your joints.
These three active ingredients are Glucosamine, chondroitin and MSM. These three natural substances have been optimally coordinated and can therefore effectively help to relieve pain, inflammation and joint stiffness.
➤ Did you know that two thirds of the German population suffer from varying degrees of osteoarthritis?
Osteoarthritis is therefore one of the most common joint diseases. It is associated with chronic wear and tear of the joint of the joint, which occurs more frequently with increasing age.
The causes include:
Contrary to the original belief, studies have now fortunately confirmed that joint cartilage can joint cartilage can regenerate and can recover from cartilage damage.
Cartilage serves to absorb pressure and shocks and protect the joints from damage. As with other tissues in the body, cartilage is also a system that is constantly busy repairing damaged cartilage cells. However, in order for this repair process to take place, the cartilage must be supplied with the right nutrients.
And this is where glucosamine and chondroitin sulphate come into play!
Glucosamine and chondroitin sulphate are important components of joint cartilage, connective tissue and ligaments. They provide the cartilage cells with important material that serves as a structural basis for the cartilage. Thanks to these two substances, people with Thanks to these two substances, people with cartilage damage can improve their mobility and flexibility, reduce pain, avoid joint inflammation and actively promote joint mobility.
Without glucosamine, our everyday movements and tasks would be difficult and painful. Our body needs glucosamine to synthesize certain proteins and fats that form important types of tissue, such as cartilage. These are then also particularly important for the development of joints, tendons and ligaments. Glucosamine also supports the formation of synovial fluid, a fluid that surrounds our joints and reliably provides important lubrication.
When taken long-term, glucosamine slows down joint wear and tear and also has other advantages over prescription painkillers. For example, it contributes to a reduction in the rate of chronic inflammatory reactions.
Chondroitin is an amino sugar that is one of the main components of cartilage. The health of the joint cartilage plays a decisive role in the occurrence of arthritis and arthrosis, as the joint cartilage is broken down during these inflammatory processes, which then leads to pain and inflammation. Certain enzymes are thought to be the cause of this breakdown. This is precisely where Chondroitin inhibits these enzymes, which deprive the body of the fluid it needs and thus helps to prevent cartilage degradation.
MSM (methylsulfonylmethane) is a natural source of sulfur that can be easily absorbed and utilized by the body. Sulphur is an important component of the protein collagen, which in turn makes up a large proportion of cartilage, connective tissue and bones as collagen-rich tissues. Together with glucosamine, MSM ensures the regeneration of damaged and worn cartilage tissue and can therefore significantly reduce joint pain.
MSM offers well-researched health benefits to patients with joint problems:
The sulphur compound MSM also influences the immune system and supports normal cell activity. This mainly involves the breakdown of by-products and excess fluid in the cells. If this process is blocked and these substances accumulate, it can lead to swelling and pain.
We know from research that osteoarthritis is a degenerative disease. It is the most common most common form of arthritis worldwide. It is associated with a breakdown of cartilage tissue, and as the disease progresses, movement becomes much more difficult and painful as more and more friction occurs in the joints.
➤ It is estimated that osteoarthritis affects over 27 million adults in the USA alone.
Numerous studies on osteoarthritis, including some in which placebos were randomly administered, clearly show that taking around 800 to 1,500 milligrams of glucosamine daily can help to minimize the symptoms of degenerative joint diseases. The pain-relieving effect usually set in within four to eight weeks. Chondroitin and MSM have also been shown to contribute to the effective relief of joint pain. Together, the three substances form an absolute power combination that declares war on joint pain and osteoarthritis.
Temporomandibular joint (TMJ) problems mainly affect young and middle-aged adults. The symptoms affect the joint that connects the jaw to the skull and normally allows us to move our head up and down and sideways without pain. Bite splints, medication and physiotherapy are normally used for treatment.
However, the more severely the joint is affected by inflammation and wear and tear, the more severe the pain becomes. As a result, those affected suffer from far-reaching restrictions and are often no longer able to speak or eat normally.
Fortunately, study results have shown that glucosamine TMJ symptoms and pain of patients suffering from arthritis of the temporomandibular joint. A Brazilian study also showed that glucosamine taken over a period of twelve weeks can reduce symptoms just as effectively as known painkillers.
Many people who suffer from aching bones, low bone density and frequent bone fractures can benefit from taking the joint formula. This is especially true for chronic joint pain or arthritis.
Study results indicate that glucosamine helps to maintain the health of the joint cartilage surrounding the bones. The substance can also pain relief, improve general physical function and improve and increase the activity level of people suffering from bone disease.
Chondroitin also helps to reduce pain in the joints to a minimum. It strengthens the resistance of the cartilage, gives it a stable structure and regulates the growth and development of the nervous system. At the same time, it contributes to optimal lubrication of the joints and can effectively minimize pain and inflammation.
Even people who are not affected by osteoarthritis can benefit from taking the joint formula. Researchers have come to the conclusion that chondroitin in combination with glucosamine helps to preserve valuable cartilage tissue cartilage tissue, alleviate pain, improve overall physical function and stimulate the and strengthen the body's important self-healing powers.
This is particularly beneficial for athletes. This is because the joint formula can significantly alleviate stress reactions in the joints after physical exertion or injury by supporting the body in the formation of new cartilage tissue. This keeps the joints remain flexible and natural inflammatory reactions under control.
➤ And the super combination can do even more! You can also benefit from the help of the wonderful joint formula for muscle pain and cramps.
MSM acts as a natural analgesic and specifically prevents muscle pain.
Scientists have successfully shown that MSM supports muscle regeneration after training, injuries and even operations. The preparation appears to be particularly effective in combination with other anti-inflammatory agents.
Why can MSM stop muscle pain and muscle damage so effectively?
This ability of MSM is based on the role that sulphur plays in the human body. The element is stored in large proportions in the tissue from which muscles and joints are formed. MSM also supports the regeneration of rigid muscle cellsthat are broken down during physical activity. This effectively prevents the muscles from swelling over a longer period of time.
MSM also restores the flexibility and permeability of the cell walls in the muscles. This means that nutrients can pass through the tissue more easily. Repair work is thus carried out much faster and the lactic acid responsible for muscle soreness after exercise can be broken down more quickly. The positive result is that the body needs less time for regeneration. In addition, pressure is relieved and sore muscles and cramps are prevented.
In case of an existing allergy to crustaceans you should first discuss with your doctor whether taking glucosamine could trigger an allergic reaction or undesirable side effects. Side effects may include Indigestion, nausea, heartburn, diarrhea, constipation, skin irritation and headaches. These are usually mild, if they occur at all.
Glucosamine is generally considered safe, especially in healthy adults. However, it may interact with drugs used as part of chemotherapy.
Chondroitin is also well tolerated. In rare cases it can cause digestive disorders such as abdominal pain, diarrhea and nausea.
Chondritin is obtained from fish, so it is not recommended to take the substance if you have a fish allergy. fish allergy is not recommended.
To date, very few side effects have been reported in relation to the intake of MSM.
Slight side effects rarely occur, such as indigestion, stomach pain or diarrhea.Patients taking blood thinners must not use MSM. Pregnant women should discuss the regular use of MSM with their doctor in advance.
Recommended joint formula:
Do not exceed the recommended daily intake.Food supplements are not a substitute for a balanced and varied diet.Store in a cool, dry place away from light. Keep out of the reach of small children.
Composition Joint formulation:
Glucosamine HCL, chondroitin sulphate, MSM, gelatine (bovine) - capsule shell
Quantities per capsule:
Allergy advice: Contains components of fish and crustaceans.
glutenfrei
laktosefrei
The joint formula helps to regenerate cartilage. This leads to pain relief.
Sources (in English):
Reginster, J. Y., Neuprez, A., Lecart, M. P., Sarlet, N. & Bruyere, O. (2012, October). Role of glucosamine in the treatment for osteoarthritis. Rheumatology International, 32(10):2959-67, doi: 10.1007/s00296-012-2416-2
Pecchi, E., Priam, S., Mladenovic, Z., Gosset, M., Saurel, A. S., Aguilar, L. et al. (2012, February). A potential role of chondroitin sulfate on bone in osteoarthritis: inhibition of prostaglandin E₂ and matrix metalloproteinases synthesis in interleukin-1β-stimulated osteoblasts. Osteoarthritis and Cartilage, 20(2):127-35, doi: 10.1016/j.joca.2011.12.002
Singh, J. A., Noorbaloochi, S., MacDonald, R. & Maswell, L. J. (2015, January). Chondroitin for osteoarthritis. The Cochrane database of systematic reviews, 1: CD005614, doi: 10.1002/14651858.CD005614.pub2
Chien, M. W., Lin, M. H., Huang, S. H., Fu, S. H., Hsu, C. Y., Yen, B. L., Chen, J. T. et al. (2015, December). Glucosamine Modulates T Cell Differentiation through Down-regulating N-Linked Glycosylation of CD25. Journal of Biological Chemistry, 290(49): 29329–29344, doi: 10.1074/jbc.M115.674671
Henrotin, Y., Mobasheri, A. & Marty, M. (2012, January). Is there any scientific evidence for the use of glucosamine in the management of human osteoarthritis?. Arthritis Research & Therapy, 14(1): 201, doi: 10.1186/ar3657
Song, K. H., Kang, J. H., Woo, J. K., Nam, J. S., Min, H. Y., Lee, H. Y. et al. (2014, January). The novel IGF-IR/Akt–dependent anticancer activities of glucosamine. BMC Cancer, 14: 31, doi: 10.1186/1471-2407-14-31
Kang, Y. H., Park, S., Ahn, C., Song, J., Kim, D. & Jin, E. J. (2015, October). Beneficial reward-to-risk action of glucosamine during pathogenesis of osteoarthritis. European Journal of Medical Research, 20: 89, doi: 10.1186/s40001-015-0176-7
Kantor, E. D., Zhang, X., Wu, K., Signorello, L. B., Chan, A. T., Fuchs, C. S. et al. (2016, November). Use of glucosamine and chondroitin supplements in relation to risk of colorectal cancer: Results from the Nurses’ Health Study and Health Professionals Follow-up Study. International Journal of Cancer, 139(9): 1949–1957, doi: 10.1002/ijc.30250
Kantor, E. D., Lampe, J. W., Peters, U., Shen, D. D., Vaughan, T. L. & White, E. (2013, June). Use of glucosamine and chondroitin supplements and risk of colorectal cancer. Cancer Causes Control, 24(6): 1137–1146, doi: 10.1007/s10552-013-0192-2
Bell, G. A., Kantor, E. D., Lampe, J. W., Shen, D. D. & White, E. (2012, August). Use of Glucosamine and Chondroitin in Relation to Mortality. European Journal of Epidemiology, 27(8): 593–603., doi: 10.1007/s10654-012-9714-6
Navarro, S. L., White, E., Kantor, E. D., Zhang, Y., Rho, J., Song, X., Milne, G. L. et al. (2015, February). Randomized trial of glucosamine and chondroitin supplementation on inflammation and oxidative stress biomarkers and plasma proteomics profiles in healthy humans. PLoS One, 10(2):e0117534, doi: 10.1371/journal.pone.0117534
Gallagher, B., Tjoumakaris, F. P., Harwood, M. I., Good, R. P., Ciccotti, M. G. & Freedman, K. B. (2015, March). Chondroprotection and the prevention of osteoarthritis progression of the knee: a systematic review of treatment agents.The American Journal of Sports Medicine, 43(3):734-44, doi: 10.1177/0363546514533777
Kim, L. S., Axelrod, L. J., Howard, P., Buratovich, N. & Waters, R. F. (2006, March). Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis and Cartilage, 14(3):286-94, doi: 10.1016/j.joca.2005.10.003
Amirshahrokhi, K. & Khalili, A. R. (2017, September). Methylsulfonylmehtane is effective against gastric mucosal injury. European Journal of Pharmacology, 811:240-248, doi: 10.1016/j.ejphar.2017.06.034
Brien, S., Prescott, P. & Lewith, G. (2011). Meta-analysis of the related nutritional supplements dimethyl sulfoxide and methylsulfonylmethane in the treatment of osteoarthritis of the knee. Evidence-based Complementary and Alternative Medicine, 2011:528403, doi: 10.1093/ecam/nep045
Parcell, S. (2002, February): Sulfur in human nutrition and applications in medicine. Alternative Medicine Review: A Journal of Clinical Therapeutic, 7(1):22-44
Debbi, E. M., Agar, G., Fichmanj, G., Ziv, Y. B., Kardosh, R., Halperin, N. et al. (2011, June). Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study. BMC Complementary and Alternative Medicine, 11:50, doi: 10.1186/1472-6882-11-50
Wang, T. W., Sun, J. S., Wu, H. C., Tsuang, Y. H., Wang, W. H. & Lin, F. H. (2006, November). The effect of gelatin-chondroitin sulfate-hyaluronic acid skin substitute on wound healing in SCID mice. Biomaterials, 27(33):5689-97, doi: 10.1016/j.biomaterials.2006.07.024
Sawitzke, A. D., Shi, H., Finco, M. F., Dunlop, D. D., Harris, C. L., Singer, N.G. et al. (2010, August). Clinical efficacy and safety of glucosamine, chondroitin sulphate, their combination, [von Google zensierter Begriff] or placebo taken to treat Osteoarthrose of the knee: 2-year results from GAIT. Annals of the Rheumatic Diseases, 69(8):1459-64, doi: 10.1136/ard.2009.120469
Kim, Y. H., Kim, D. H., Lim, H., Baek, D. Y., Shin, H. K. & Kim, J. K. (2009, April). The anti-inflammatory effects of methylsulfonylmethane on lipopolysaccharide-induced inflammatory responses in murine macrophages. Biological & Pharmaceutical Bulletin, 32(4):651-6
Barmaki, S., Bohlooli, S., Khoshkhahesh, F. & Nakhostin-Roohi, B. (2012, April). Effect of methylsulfonylmethane supplementation on exercise - Induced muscle damage and total antioxidant capacity. The Journal of Sports Medicine and Physical Fitness, 52(2):170-4
Nakhostin-Roohi, B., Niknam, Z., Vaezi, N., Mohammadi, S. & Bohlooli, S. (2013). Effect of single dose administration of methylsulfonylmethane on oxidative stress following acute exhaustive exercise. Iranian Journal of Pharmaceutical Research, 12(4):845-53
Lee, H. R., Cho, S. D., Lee, W. K., Kim, G. H. & Shim, S. M. (2014). Digestive recovery of sulfur-methyl-L-methionine and its bioaccessibility in Kimchi cabbages using a simulated in vitro digestion model system. Journal of the Science of Food and Agriculture, 94(1):109-12, doi: 10.1002/jsfa.6205
Usha, P. R. 6 Naidu, M. U. (2004). Randomised, Double-Blind, Parallel, Placebo-Controlled Study of Oral Glucosamine, Methylsulfonylmethane and their Combination in Osteoarthrose. Clinical Drug Investigation, 24(6):353-63
Kalman, D. S., Feldman, S., Scheinberg, A. R., Krieger, D. R. & Bloomer, R. J. (2012, September). Influence of methylsulfonylmethane on markers of exercise recovery and performance in healthy men: a pilot study. Journal of the International Society of Sports Nutrition, 9(1):46, doi: 10.1186/1550-2783-9-46.
Jerosch, J. (2011). Effects of Glucosamine and Chondroitin Sulfate on Cartilage Metabolism in OA: Outlook on Other Nutrient Partners Especially Omega-3 Fatty Acids. International Journal or Rheumatology, 2011: 969012, doi: 10.1155/2011/969012
Ronca, F., Palmieri, L., Panicucci, P. & Ronca, G. (1998, May). Anti-inflammatory activity of chondroitin sulfate. Osteoarthrose and Cartilage, 6 Suppl A:14-21
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Joint formula - high dosage - all in one capsule - laboratory tested - free from additives