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S-acetyl-L-glutathione is a form of acetylated glutathionewhich as one of the strongest antioxidants worldwide. Glutathione is an endogenous protein that is produced in the liver and is required by every cell in the body. It is extremely effective in protecting body cells, tissues and organs and prevents them from being damaged by harmful substances and toxins. With increasing age, however, the glutathione level in the cells decreases and production in the liver also decreases by around 10 % every ten years.
Supplementation with our S-acetyl-L-glutathione is particularly recommended when it comes to preventing a drop in glutathione levels.
S-acetyl-L-glutathione can therefore provide you with the best possible support with its many positive effects on your health:
Acetylated glutathione is the promising innovation in the field of glutathione supplements that many people have long been waiting for. It is characterized by a very high bioavailability and, unlike foods containing glutathione, can even cross the blood-brain barrier. cross the blood-brain barrier. This means that our S-acetyl-L-glutathione is not held back by this barrier, but can penetrate directly to the brain and unfold its beneficial effects there. This means that the full potential of glutathione is available to your body - and at a fraction of the cost of intravenous treatment.
Numerous studies have already shown that acetylated glutathione leads to a rapid increase in glutathione levels in the cells. This form of glutathione is therefore clearly more effective and faster than normal glutathione.
In addition to the natural depletion of S-acetyl-L-glutathione described above, there are other factors that cause glutathione levels in the body to drop: These include diseases that challenge the body, medication intake and, above all, environmental toxins and pollutants. Alcohol consumption can also impair the natural production of glutathione.
Disorders of the glutathione level are also repeatedly associated with the progression of serious diseases such as cancer, cardiovascular diseases and disorders of the immune or digestive system have been linked. The link between chronic diseases and low glutathione levels is also becoming increasingly clear.
For this reason, many scientists consider glutathione to be the most important antioxidant in the fight against disease and the ageing process.
If you consider the diseases with which a low glutathione level is associated, it quickly becomes clear how important it is to have sufficient amounts of glutathione in the body.
The following groups of people in particular are often affected by low glutathione levels:
Free radicals are substances that are produced by metabolic processes and damaging external influences, such as environmental toxins or UV radiation. They attack the body at the cellular level, set off chain reactions and thus impair our health and well-being. S-acetyl-L-glutathione is probably not well received by them, as glutathione can successfully prevent this with its health-promoting effects. S-acetyl-L-glutathione supports the body with the following effects, among others:
And glutathione not only neutralizes free radicals itself. This highly effective antioxidant also reactivates other antioxidants such as vitamins C and E. After these vitamins have successfully neutralized free radicals, they normally become unstable radicals themselves. Glutathione effectively contributes to their reactivation so that they can continue to function as antioxidants.
Glutathione also plays an important role in strengthening the immune system and helps to protect cells from the damaging effects of oxidative stress and toxins.
The substance can support the immune system in two ways: Basically, glutathione plays a central role in the work of the so-called T-cells or lymphocytes - these are the important white blood cells that fight pathogens on the front line. Glutathione is able to significantly increase their numbers. Furthermore, research results indicate that glutathione also stimulates the production and activity of natural killer cells. These are the cells of the immune system that are responsible for killing infected cells or cancer cells.
Glutathione also effectively supports the functions of the liver, kidneys, digestive system and intestines - in other words, all organs that play an important role in detoxifying the body. Glutathione can work in two different ways:
The substance is therefore crucially involved in the detoxification that takes place in the liver. There it binds toxins so that they can be effectively excreted from the body. The detoxifying effect of glutathione is so strong that patients who have to be hospitalized after an overdose of Tylenol (paracetamol) are given the substance intravenously. The additionally supplied glutathione is then available in the liver to break down excess paracetamol.
In addition, glutathione has been shown to be a significant factor in the excretion of heavy metals such as mercury, cadmium and arsenic. In this regard, studies on mammalian kidney cells have shown that glutathione is as effective as DMSA in reducing mercury in kidney cells - these are drugs that are used as standard to break down heavy metals.
Balancing glutathione levels also helps to reduce chronic inflammation and can even restore immune function.
High levels of inflammation occur simultaneously in practically all chronic diseases such as diabetes, heart disease and cancer. However, inflammation is also useful and necessary in short bursts in order to effectively fight infectious invaders. Injuries can also trigger an inflammatory reaction. However, if our body is weakened by environmental toxins, unhealthy lifestyle habits or stress, inflammation cannot simply subside as it should. This is why many people suffer from chronic inflammation. This is where S-acetyl-L-glutathione capsules can provide effective relief.
This is because glutathione is involved in the control of inflammatory processes and determines when inflammation increases or decreases by influencing the lymphocytes. Incidentally, this mechanism is completely independent of the antioxidant properties of the substance.
According to a study published in 2013 in the journal Biochimica Et Biophysica Acta glutathione can also be effective in fighting microbial, viral and parasitic infections. This is made possible by strengthening the functional activity of immune cells and significantly improving both innate and acquired immunity.
Brain cells have a particularly high high demand for glutathione. Countless studies have shown that every type of mental disorder is associated with oxidative stress in the brain. Researchers have discovered that low glutathione levels play an important role in both the onset and development of Parkinson's disease and that Alzheimer's disease is also closely linked to the reduction of glutathione and other important antioxidants in nerve cells.
Fortunately supports Glutathione not only numerous functions that are essential for a healthy heartbut can also effectively prevent heart attacks and other heart diseases.
If our body does not have enough glutathione available to repair and prevent damage to the arteries, there is an increased risk of heart disease and cardiovascular disease.
In fact, almost all heart diseases begin with the accumulation of plaque on the artery walls. Bad cholesterol, known as LDL, oxidizes and damages the inner walls of blood vessels by forming atherosclerotic plaque.
If these plaques eventually rupture and break off, this can lead to blockage of blood vessels and obstruction of blood flow, which then triggers heart attacks or strokes.
With the help of an enzyme called glutathione peroxidase, glutathione is able to effectively stop the cell-damaging free radicals that impair our health. In this way, the substance helps to prevent damage to the heart and has been proven to reduce the risk of a heart attack.
Glutathione is a substance produced naturally in the body, so side effects are very rare. However, long-term intake of glutathione capsules could lead to a reduction in zinc levels.
The rare but possible side effects include
As alcohol contributes to lowering the glutathione level, it is highly advisable to avoid alcohol while taking glutathione capsules, as otherwise the effect will be reduced or impaired.
Recommended intake S-Acetyl-Glutathione Capsules:
As a dietary supplement, take one capsule twice daily with plenty of water. Preferably half an hour before meals.
Do not exceed the recommended daily intake.Not a substitute for a balanced and varied diet.Store in a cool, dry place away from light. Keep out of the reach of small children.
Composition of glutathione capsules:
EMOTHION® S-Acetyl-L-Glutathione, cellulose, hydroxypropylmethylcellulose (vegan capsule shell)
Quantities per capsule
glutenfrei
laktosefrei
ohnegelatin
vegan
Glutathione is produced by the body. The highest concentration is found in the liver. Glutathione helps to detoxify the body and also counteracts cell damage. It is one of the most powerful antioxidants, strengthens the immune system and slows down the ageing process.
Yes, because the patented raw material EMOTHION® has a faster dissolution rate and therefore more effective and efficient oral absorption. This ensures excellent bioavailability.
The patented raw material EMOTHION® S-Acetyl-Glutathione has a significantly better bioavailability compared to conventional glutathione preparations.
Sources (in English):
Patrick L. (2002). Mercury toxicity and antioxidants: Part 1: role of glutathione and alpha-lipoic acid in the treatment of mercury toxicity. Alternative medicine review : a journal of clinical therapeutic, 7(6), 456–471.
Okun, J. G., Sauer, S., Bähr, S., Lenhartz, H. & Mayatepek, E. (2004). S-Acetylglutathione normalizes intracellular glutathione content in cultured fibroblasts from patients with glutathione synthetase deficiency. Journal of Inherited Metabolic Disease, 27(6):783-6
Locigno, R., Pincemail, J., Henno, A., Treusch, G. & Castronov, V. (2002, January). S-acetyl-glutathione selectively induces apoptosis in human lymphoma cells through a GSH-independent mechanism. International Journal of Oncology, 20(1):69-75
Vogel, J. U., Cinatl, J., Dauletbaev, N., Buxbaum, S., Treusch, G. & Cinatl, J. Jr. (2005, January). Effects of S-acetylglutathione in cell and animal model of herpes simplex virus type 1 infection. Medical Microbiology and Immunology, 194(1-2):55-9, doi: 10.1007/s00430-003-0212-z
Pizzorne, J. (2014, February). Glutathione! Integrative Medicine: A Clinician's Journal, 13(1): 8–12
Biswas, S. K. & Rahman, I. (2009). Environmental toxicity, redox signaling and lung inflammation: the role of glutathione. Molecular Aspects of Medicine, 30(1-2):60-76, doi: 10.1016/j.mam.2008.07.001
Marí, M., Morales, A., Colell, A., García-Ruiz, C. & Fernández-Checa, J. C. (2009, November). Mitochondrial glutathione, a key survival antioxidant. Anitoxidant & Redox Signaling, 11(11):2685-700, doi: 10.1089/ARS.2009.2695
Fraternale, A., Paoletti, M. F., Casabianca, A., Oiry, J., Clayette, P., Vogel, J. U. et al. (2006). Antiviral and immunomodulatory properties of new pro-glutathione (GSH) molecules. Current Medicinal Chemistry, 13(15):1749-55
Fraternale, A., Brundu, S. & Magnani, M. (2017, February). Glutathione and glutathione derivatives in immunotherapy. Biological Chemistry, 398(2):261-275, doi: 10.1515/hsz-2016-0202
Wu, G., Fang, Y. Z., Yang, S., Lupton, J. R., Turner, N. D. (2004, March). Glutathione metabolism and its implications for health. The Journal of Nutrition, 134(3):489-92, doi: 10.1093/jn/134.3.489
Dröge, W. & Breitkreutz, R. (2000, November). Glutathione and immune function. The Proceedings of the Nutrition Society, 59(4):595-600
Balendiran, G. K., Dabur, R. & Fraser, D. (2004). The role of glutathione in cancer. Cell Biochemistry and Function, 22(6):343-52, doi: 10.1002/cbf.1149
Ballatori, N., Krance, S. M., Notenboom, S., Shi, S., Tieu, K. & Hammond, C. L. (2009, March). Glutathione dysregulation and the etiology and progression of human diseases. Biological Chemistry, 390(3):191-214. doi: 10.1515/BC.2009.033
Richie, J. P. Jr., Nichenametla, S., Neidig, W., Calcagnotto, A., Haley, J. S., Schell, T. D. et al. (2015, March). Randomized controlled trial of oral glutathione supplementation on body stores of glutathione. European Journal of Nutrition, 54(2):251-63, doi: 10.1007/s00394-014-0706-z
Schreck, R., Rieber, P. & Baeuerle, P. A. (1991, August). Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-kappa B transcription factor and HIV-1. The EMBO Journal, 10(8):2247-58
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S-Acetyl Glutathione Capsules - 100% pure reduced glutathione - patented premium active ingredient