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Ubiquinol is the active form of coenzyme Q10 (CoQ10), which our body can produce itself. As a powerful antioxidant it helps with many diseases associated with the ageing process associated with the ageing process. CoQ10 is found in almost every single cell and tissue in our body. There it fulfills important functions, such as supplying the cells with energy, the transport of electrons and the regulation of blood pressure.
Ubiquinol capsules are suitable for:
The coenzyme with the broad spectrum of activity is available in two different forms:
Many people take Q10 supplements to boost their health. However, they do not know that there are two different forms of this essential nutrient and that each of these forms performs very specific functions in the body.
When talking about CoQ10, most people refer to ubiquinone, which was the only form of the coenzyme commercially available until 2007. Only then did the more effective form ubiquinol enter the health market.
An important difference between the two forms is that conventional ubiquinone must first be converted into ubiquinol by the body before it can be used to produce cellular energy for the heart and other important organs. In contrast to conventional CoQ10, ubiquinol also has strong antioxidant properties and effectively neutralizes free radicals that could otherwise damage healthy cells in the body. However, from the age of thirty, the body finds it increasingly difficult to convert CoQ10 into ubiquinol.
Every cell in our body is constantly producing energy to keep us healthy and vital. This energy comes in the form of the molecule ATP and is produced in the mitochondria - the energy powerhouses of our cells. The mitochondria convert fats and nutrients into ATP - but to do this they need ubiquino
➤ Did you know that the production of ATP is the body's most important source of energy?
Ubiquinol not only supports the body's own energy production, but is also considered one of the most powerful antioxidants available. As such, it has the wonderful ability to effectively protect the body's cells from damagecaused by oxidative stress and free radicals. In this way, the coenzyme helps the body to heal itself and restore itself to the best possible state of health.
And as a powerful antioxidant, coenzyme Q10 can even increase the absorption of other essential nutrients. Here, it has been shown to help recycle vitamin C and vitamin E in particular, further maximizing their effects.
The energy produced by the mitochondria is required by the body for three basic functions of the heart:
The heart has the highest energy requirement in the entire body. The ventricle needs energy to contract and pump blood through the arteries. However, even more energy is needed to relax the heart muscle. This is how the heart therefore a large amount of cellular energy to function in order to function properly. If this energy in the form of ATP is not available in sufficient quantities, heart function is impaired. This is why it is so important that the mitochondria always have enough ubiquinol available.
➤ These research results make it convincingly clear why ubiquinol is considered "the nutrient of the new century".
In principle, ubiquinol is produced by the body itself. However, as the body's stores continue to diminish with age, taking ubiquinol capsules can help to replenish the body's reserves. The coenzyme also boosts energy production and thus makes an important contribution to general heart health. general heart health.
Statins, or cholesterol-lowering drugs, are among the best-selling medications worldwide. They have proven to prevent cardiovascular problems such as heart attacks by lowering the "bad" LDL cholesterol; at the same time, however, they also reduce the ubiquinol content in the muscles, which also has an effect on heart health.
Why do drugs that are so effective at lowering cholesterol levels also contribute to depleting the body's CoQ10 stores?
Quite simply because cholesterol and ubiquinol are produced by our body in almost the same way. And ubiquinol, which plays an important role in heart health, is even transported through the blood via the cholesterol molecules.
A study on this topic published in the Journal of the American Medical Association showed a 22% reduction in ubiquinol levels in patients taking a known statin, while other studies suggest that statins can reduce coenzyme Q10 levels by up to 40%. The long-term use of cholesterol-lowering drugs can thus increase the risk of nerve damage and muscle weakness increase.
Since nerves and muscle tissue require large amounts of ubiquinol or coenzyme Q10 to maintain energy production, it is understandable that a corresponding deficiency can lead to problems. There is already research into whether and to what extent ubiquinol can prevent muscle pain after the use of statins. So far, experience suggests that it makes sense for patients taking cholesterol-lowering drugs to give their body coenzyme Q10 at the same time, to simultaneously supply their bodies with coenzyme Q10 in the form of ubiquinol as a dietary supplement.
Ubiquinol can also have a beneficial effect when it comes to blood pressure. Double-blind studies on this topic have shown that the additional intake of coenzyme Q10 in various forms can help to significantly reduce the blood pressure of people with hypertension. significantly reduce the blood pressure of people with hypertension (high blood pressure).
In this context, a daily dose of 100 mg of the regular ubiquinol form of coenzyme Q10 for at least ten weeks has proven to be effective. The authors of these studies confirm that treatment with coenzyme Q10 can effectively lower blood pressure by reducing oxidative stress. oxidative stress. In addition, it is even said to blood sugar release in high blood pressure patients who are taking conventional blood pressure medication. This is because blood sugar levels are regulated by the blood sugar hormone - and a high level of the blood sugar hormone combined with high blood pressure can increase the risk of heart attacks by a factor of twenty.
The fact that ubiquinol makes a valuable contribution to a healthy healthy cardiovascular system is now generally known and recognized. Therefore, patients who take statins to lower cholesterol should definitely also supplement ubiquinol if they want to do something good for their health. Statins actually inhibit the production of ubiquinol in the body, which often results in a deficiency. The patients affected then suffer from symptoms such as muscle pain and tiredness, which are triggered by the deficiency.
Recent research results even show that ubiquinol also has a surprisingly positive effect on cholesterol levels. positive influence on cholesterol levels. has. German scientists carried out a study to determine the effects of ubiquinol on the level of LDL, i.e. bad cholesterol. They came to the positive conclusion that ubiquinol can absolutely keep up with secondary plant substances in terms of its effectiveness, and that it even leads to a reduction in the LDL levels by an average of 12.7 percent. on average.
Oxidative stress can not only lead to cell damage, but also to metabolic diseases such as diabetes.
The resulting insulin resistance is associated with abnormal mitochondrial function. Ubiquinol has been shown to improve insulin sensitivity and thereby regulate regulate blood glucose levels.
Supplementation with ubiquinol can also help to increase the CoQ10 concentration in the blood of diabetes patients, who normally have low levels, by a factor of three.
In one study, people with type 2 diabetes took CoQ10 for twelve weeks. This not only significantly reduced the fasting blood glucose level, but also the hemoglobin A1C - i.e. the average blood glucose level over the last two to three months.
Ultimately, ubiquinol could even contribute to the prevention of diabetesby stimulating the stimulating the breakdown of fat and reducing the accumulation of fat cells that can lead to obesity and also type 2 diabetes.
Our brain cells are mainly supplied with energy by the mitochondria as the most important energy producers.
However, the performance of the mitochondria declines with increasing age. If they lose their function, this can lead to the death of brain cells and result in diseases such as Alzheimer's and Parkinson's. Unfortunately, our brain is very susceptible to oxidative damage as it has both a high fatty acid content and a high oxygen demand.
Oxidative damage then contributes to the formation of harmful compounds that impair memory performance as well as cognitive and physical functions.
Ubiquinol can fortunately contribute to the formation of fewer harmful compounds and thus even slow down the development and progression of Alzheimer's or Parkinson's disease.
Certain diseases, such as cancer, develop more easily in a body that has trouble maintaining an optimal pH level. However, ubiquinol has the amazing ability to transport proteins across membranes within cells and separate certain digestive enzymes from the rest of the cell. Thus, it makes a valuable contribution to maintaining an optimal pH level in the body, which, in addition to the strong antioxidant power of the coenzyme, could be another reason why the risk of cancer is lower in people with a higher CoQ10 level.
The female fertility unfortunately continues to decline with increasing age. This is mainly due to the fact that the number and quality of available egg cells decreases. Ubiquinol is directly involved in this process, as the production of CoQ10 also declines in the body with increasing age. As a result, the egg cells can no longer be effectively protected against oxidative damage.
Taking CoQ10 supplements appears to stop this age-related loss of oocytes. loss of egg cells and can even and can even reverse damage.
In a similar way sperm are also susceptible to oxidative damage, which causes a decline in their number and quality, ultimately leading to infertility.
In several studies, scientists have come to the conclusion that taking CoQ10 supplements can improve the the quality, number and concentration of sperm by effectively boosting antioxidant protection.
If the function of the mitochondria is impaired, this can lead to various problems: More harmful free radicals are produced, the protection provided by antioxidants decreases and the cells absorb more calcium. As a result, the brain cells have too little energy available available to the brain cells, which leads to headaches and even migraines. can result.
However, scientists have shown that ubiquinol promotes mitochondrial function and is also effective in reducing inflammation that can occur during migraine attacks.
In a study with 42 test subjects, it became clear that taking CoQ10 was able to reduce the frequency of migraine attacks three times better than a placebo. A CoQ10 deficiency is also frequently observed in migraine patients.
Scientists in a large study involving more than 1550 test subjects with low CoQ10 levels were also able to show that the participants suffered fewer headaches after treatment with CoQ10 supplements.
Ubiquinol is therefore not only suitable for treating migraine attacks, but also for effectively preventing them.
Although ubiquinol is generally considered to be very safe and has been used in medicine for many years, it can cause side effects in some people.
The possible side effects of CoQ10 include
When should you refrain from taking ubiquinol?
If you are pregnant or breastfeedingit is advisable not to take ubiquinol supplements, as it is not known whether the substance is safe or not in these cases.
Coenzyme Q10 supplements can also reduce the anticoagulant effect of statins and common cholesterol-lowering drugs. In this case, please consult your doctor before taking ubiquinol.
Recommended intake Ubiquinol 100mg:
Do not exceed the recommended daily intake.Food supplements are not a substitute for a balanced and varied diet.Store in a cool, dry place away from light. Keep out of the reach of small children.
Composition Ubiquinol 100mg:
Canola oil, diglyceryl monooleate, Kaneka QHS ubiquinol (active coenzyme Q10), beeswax, soy lecithin (GMO-free), capsule shell (maize starch, glycerine, carrageenan, caramel, disodium phosphate)
Quantities per capsule:
glutenfrei
laktosefrei
ohnegelatin
Ubiquinone is the better-known form of the coenzyme. Ubiquinol, on the other hand, is the active and more readily available form and is therefore more suitable.
Sources (in English):
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Langsjoen, P. H. & Langsjoen, A. M. (2015, January). Comparison study of plasma coenzyme Q10 levels in healthy subjects supplemented with ubiquinol versus ubiquinone. Clinical Pharmacology in Drug Development, 3(1):13-7, doi: 10.1002/cpdd.73
Yang, Y. K., Wang, L. P., Chen, L., Yao, X. P., Yang, K. Q., Gao, L. G. et al. (2015, October). Coenzyme Q10 treatment of cardiovascular disorders of ageing including heart failure, hypertension and endothelial dysfunction. Clinica Chimica Acta; International Journal of Clinical Chemistry, 450:83-9, doi: 10.1016/j.cca.2015.08.002
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Fischer, A., Onur, S., Niklowitz, P., Menke, T., Laudes, M. & Döring, F. (2016, May). Coenzyme Q10 redox state predicts the concentration of c-reactive protein in a large caucasian cohort. Biofactors, 42(3):268-76. doi: 10.1002/biof.1269
Hosoe, K., Kitano, M., Kishida, H., Kubo, H., Fujii, K. & Kitahara, M. (2007, February). Study on safety and bioavailability of ubiquinol (Kaneka QH) after single and 4-week multiple oral administration to healthy volunteers. Regulatory Toxicology and Pharmacology, 47(1):19-28, doi: 10.1016/j.yrtph.2006.07.001
Failla, M. L., Chitchumroonchokchai, C., Aoki, F. (2014, July). Increased bioavailability of ubiquinol compared to that of ubiquinone is due to more efficient micellarization during digestion and greater GSH-dependent uptake and basolateral secretion by Caco-2 cells. Journal of Agricultural and Food Chemistry, 62(29):7174-82. doi: 10.1021/jf5017829
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Kaneka Ubiquinol Q10 Capsules - CoQ10 - active coenzyme Q10